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The collection consists of speeches, reports, publications, research notes, and correspondence. The bulk of the collection relates to Wu's involvement in the American Physical Society as well as her research activities. The correspondence is chiefly professional, relating to C. S. Wu's physics research, professional commitments, appointments, meetings, conferences, and publications. Correspondence also includes letters from individuals around the world praising Wu for her accomplishments, asking advice, arranging speaking engagements, discussing administrative matters, and trading research notes, as well as information on publications and other topics. In addition, the collection contains information on Wu's involvement in the development of an affirmative action program at Columbia University in the 1970's.

Correspondence, manuscripts, lectures, notes, diaries, notebooks, reports, financial records, blueprints, photographs, and printed materials of Y.C. James Yen and the IIRR concerned with the development, sharing, and financing innovative methods of teaching, improving agriculture, health and family planning, and education in impoverished villages. Among the cataloged correspondents are: Pearl Buck, William O. Douglas, Nelson Rockefeller, and DeWitt Clinton.