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The collection consiste of correspondence, memoranda, reports, bulletins, clippings, photographs, awards, and printed material. The files, arranged by genre and topic and reflect her philanthropic and legislative work in the areas of health, specifically cancer, heart disease, and mental health. Her civic and legislative work is covered in detail, as well as her private interests and activities.

The collection consists of the editorial and production archives of Random House, Inc. from its founding in 1925 to the 1990s. The correspondence and editorial files include many of the prominent novelists and short story writers from 20th-century American and European literature: Saul Bellow; Erskine Caldwell; Truman Capote; William Faulkner; Sinclair Lewis; André Malraux; Gertrude Stein and Thornton Wilder. Among the poets there are files for W. H. Auden; Allen Ginsberg; Robinson Jeffers; Robert Lowell; and Stephen Spender. In the area of theater there are files for Maxwell Anderson; Moss Hart; Lillian Hellman; Eugene O'Neill; and Tennessee Williams. Random House transacted business with many fine presses and noted typographers and the archives contain files for Nonesuch Press, Grabhorn Press and Golden Cockerel Press, as wll as for Bruce Rogers, Valenti Angelo, and Edwin, Jane, and Robert Grabhorn.

Correspondence with many well known authors and scientists, correspondence with publishers, contracts, and other materials dealing with the many series of books which she has organized. Dr Anshen has edited over one hundred works in fields ranging from physics and biology to philosophy, education, psychology, and esthetics. Her series - WORLD PERSPECTIVES (Harper), RELIGIOUS PERSPECTIVES (Harper), CREDO PERSPECTIVES (Pocket Books/Simon & Schuster), THE SCIENCE OF CULTURE SERIES (Harcourt, Brace), PERSPECTIVES IN HUMANISM (World Pub. Co.), and THE TREE OF LIFE SERIES - have been concerned with new trends in scientific thought and the mutual intelligibility of the various arts and sciences. A new series, CONVERGENCE (Columbia University Press), was started in 1981 dealing with ideas that changed, or that are changing the world. Books from the various series are also included. There is also personal material of Dr Anshen and her family.